More like Down in the Bottomlands

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The Andromeda StrainSeries
series2 books1969
Tense in tone, about plague and pandemic.
“Daniel H. Wilson's authorized 2019 sequel The Andromeda Evolution revisits the same threat five decades later.”
from the catalogue
Start with The Andromeda Strain →
Eden (Harry Harrison)Series
series5 books1984
completed
About war and aliens, set in prehistoric.
“Harry Harrison's Eden trilogy imagines an Earth where the dinosaurs never died out, evolving instead into the Yilane, a technologically advanced reptilian civilization that shares the planet uneasily with early humans.”
from the catalogue
Start with West of Eden →
The WandererNovel
Fritz Leiberstandalone novel1964
Tense in tone, about aliens, set in our world and space.
The Sound of His HornNovel
Sarbanstandalone novel1952
Dystopia and time travel, dark in tone, about totalitarianism.
FootfallNovel
Larry Niven & Jerry Pournellestandalone novel1985
Alien invasion, tense in tone, about aliens, set in our world.
“When aliens travel to Earth from Alpha Centauri, differences between alien and human psychology result in an unprovoked invasion, and the resulting resistance results in the aliens' use of a devastating weapon.”
from the catalogue
DreamcatcherNovel
Stephen Kingstandalone novel2001
Horror and alien invasion, tense in tone, about aliens.
“According to the author in his afterword, the working title was Cancer.”
from the catalogue