More like Prime Directive

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DuneUniverse
universe78 books1963
Science fiction and space opera, about political intrigue, set in far future and other star systems.
“The desert planet, where empire runs on a single substance: the spice melange, which folds space, prolongs life, and unlocks prescience, and which exists nowhere else in the known universe.”
from the catalogue
Start with Dune →
includes Dune, Heroes of Dune, Dune Prequels, Dune Sequels, Background of the Dune Universe
FoundationUniverse
universe123 books1940
About robots.
“There is a science that reads the future of quadrillions the way an astronomer reads the orbits of stars.”
from the catalogue
Start with Foundation →
includes Trantorian Empire, Foundation, The Collected Fiction of Isaac Asimov, Second Foundation Trilogy, The Positronic Robot Stories, Foundation (Original Stories)
CoDominiumUniverse
universe98 books1971
Military science fiction.
“The body of work runs along a few hard threads rather than one line.”
from the catalogue
Start with The Mote in God's Eye →
includes Moties, Laurie Jo Hansen, Falkenberg's Legion, War World
The Dosadi ExperimentNovel
Frank Herbertstandalone novel1977
About aliens and survival.
“Dosadi is rumored to be an experimental planet, and the experimenters are the froglike Gowachin, whose culture is founded upon a strange legal system in which McKie is the only human ever trained.”
from the catalogue
Alliance-UnionUniverse
universe173 books1976
Science fiction, set in far future.
“Around that spine cluster the merchanter novels of trader Families, the Faded Sun trilogy of human envoys among the martial alien Mri, and the Chanur books, narrated from the hierarchical, whiskered viewpoint of the hani.”
from the catalogue
Start with Heavy Time →
includes Chanur, Company Wars, The Hinder Stars, Hanan Rebellion, Mri Wars, Unionside, Era of Rapprochement, Age of Exploration
HonorverseUniverse
universe83 books1993
Military science fiction.
“At the center stands one officer, Honor Harrington — captain, then something far larger — and the six-limbed empathic treecat who rides her shoulder.”
from the catalogue
Start with On Basilisk Station →
includes Honor Harrington, Saganami Island, Expanded Honorverse, Wages of Sin, Worlds of Honor anthologies, Manticore Ascendant, Star Kingdom (Honor Harrington), Honor Harrington Universe short fiction